How Covid kills
In Episode #25 of The Art of Medicine with Dr. Andrew Wilner, I had the pleasure of speaking with Maureen Czick, MD. Dr. Czick is a locum tenens anesthesiologist and author of an intriguing publication that explores the role of the renin-angiotensin system (RAS) in the pathophysiology of COVID-19 (Czick et al. 2020).
Dr. Czick shared how locum tenens returned “agency” to her life, which allowed her to spend more time with her family and pursue other interests, such as writing. We also discussed her recent paper, which illustrates how RAS dysfunction might be the key to understanding the pathophysiology of COVID-19.
The RAS hypothesis is provocative because we already have medications, such as the antihypertensive losartan (Cozaar), that act on RAS and could potentially improve the disease’s morbidity and mortality.
Please join me during this fascinating 25-minute interview with Dr. Maureen Czick.
Reference Czick et al. COVID’s Razor: RAS imbalance, the common denominator across disparate, unexpected aspects of COVID-19. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2020;13:3169-3192.